Grimsby inflicted more misery on League Two's basement club Cheltenham with a 7-1 victory over nine men at Blundell Park.
Managerless Cheltenham briefly threatened an upset by taking an early lead, but two stunning Jamie Walker strikes and a pair of red cards turned the contest into a rout.
Cheltenham's Early Lead Wiped Out by Walker's Double
The visitors did take the lead in the 19th minute as Isaac Hutchinson finished off Ethon Archer's low cross.